بررسی رابطه لیپیدهای سرم و شدت ادم ماکولا در افراد مبتلا به دیابت

Background and purpose: Macular edema is a common causes of visual imparity in diabetic patients. Several studies to evaluate ways to prevent and slow down its progression have been done. This study to determine serum lipids, accelerate the creation and macular edema was performed. Materials and methods: Blood serum lipids in 180 diabetic patients referred to eye clinic of Shahid Beheshti Hospital was evaluated. Data obtained from patients were classified in three groups: diabetic retinopathy without macular edema (group 1), patients with mild diabetic retinopathy with macular edema (Group 2) and patients with diabetic retinopathy with macular edema and hard exudates (group 3). Then laboratory values were collected and analyzed by version 18 statistical software spss. For data parametric ÂNÔVÂ test and then Tukey test was used. P.value less than 0.05 were considered significant. Results: Total cholesterol in groups 1, 2 and 3 were 402.53 ± 95.202, 213.52 ± 17.204 and 201.113 ± 74.228, respectively (P>0.05). The mean HDL in groups 1, 2 and 3 were 586.15 ± 25.44, 920.22 ± 32.47 and 009.11 ± 49.48, respectively. The mean VLDL in groups 1, 2 and 3 were 396.22 ± 09.37, 238.20 ± 85.36 and 127.15 ± 51.33, respectively (P>0.05). The mean TG in groups 1, 2 and 3 were 911.227 ± 74.212, 448.109 ± 43.187 and 741.238 ± 28.218, respectively (P>0.05). The mean LDL level in group 3 (132.33 ± 53.75) was statistically higher than group 1 (113.39 ± 38.48) and group 2 (113.08 ± 42.08) (P<0.05). Çonclusion: The results of this study showed that, serum LDL, the intensity of macular edema and hard exudates plaques, are associated.